After Khan's victory, he was ranked second, behind only Joel Casamayor.
Following the fight, Khan split from his trainer Oliver Harrison, the trainer for all of his previous 17 professional contests.
Gomez, a super featherweight champion who was reaching the end of his career and had lost the last one of his six fights, was described as a "backward step" in Khan's quest for a world title.
Khan stated "I think I'm above this level now" and made it clear that he expected a fast and explosive finish to the fight knocking down Gomez two times in the fight and a great finish.
Instead of holding, Khan tried to punch back, but instead was punched on the head by a left hook, right hook combo, sending him crashing to the canvas. Prescott ended it for good with another left that put Khan down again. Following his defeat to Prescott, Frank Warren sacked Khan's trainer Jorge Rubio and replaced him with Freddie Roach.
In early August, the lightweight Breidis Prescott was chosen by Rubio as Khan's next opponent.
However, after the fight, Khan said he felt he had moved up a level by "fighting a good fighters like Gomez".
Khan received criticism for being knocked down in the second round, but proved his resilience by coming back stronger after this.
He is a former unified light-welterweight world champion, having held the WBA (later Super) title from 2009 to 2012, and the IBF title in 2011.
Additionally he held the Commonwealth lightweight title from 2007 to 2008, the WBC Silver welterweight title from 2014 to 2016, and has challenged once for a middleweight world title in 2016.